jiyunshin
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gin commit from DESKTOP-593CF0Q
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3 years ago | |
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| Fig. S7A&B.mat | 3 years ago | |
| Fig. S7C&D.mat | 3 years ago | |
| README.md | 3 years ago | |
README.md
Data for Figure S7
Fig. S7A&B.mat
Number of the significantly modulated bins in PSTHs of L5 pyramidla neurons in control and hM4Di/CNO mice.
Conditions
| Condition | Description |
|---|---|
| Ctrl | Cells from control mice without hM4Di expression but with CNO application in L1 of S1. |
| Dreadd | Cells from hM4Di/CNO mice with hM4Di expression & with CNO application in L1 of S1. |
Entries
| Entry | Description |
|---|---|
<cond>FreqSigBins |
Number of significantly modulated bins from PSTHs of firing rate responses. |
<cond>BurstSigBins |
Number of significantly modulated bins from PSTHs of burst rate responses. |
Fig. S7C&D.mat
Average firing and burst responses of L5 pyramidal neurons in control and hM4Di/CNO mice. First column: baseline activity - [-1 0] s from stimulus onset. Second column: post-stimulus activity - [0.2 2.5] s from stimulus onset.
Conditions
| Condition | Description |
|---|---|
| Control | Cells from control mice without hM4Di expression but with CNO application in L1 of S1. |
| DREADD | Cells from hM4Di/CNO mice with hM4Di expression & with CNO application in L1 of S1. |
Entries
| Entry | Description |
|---|---|
<cond>_freq |
Firing rate responses in each condition. |
<cond>_burst |
Burst rate responses in each condition. |
| datacite.yml | |
|---|---|
| Title | Perirhinal input to neocortical layer 1 controls learning |
| Authors |
Doron,Guy;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0003-1252-5747
Shin,Jiyun N.;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0002-0534-6938 Takahashi,Naoya;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany. Present address: University of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience, IINS, UMR 5297, 33000 Bordeaux,France.;ORCID: 0000-0002-6008-4627 Drüke,Moritz;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0002-6787-9377 Bocklisch,Christina;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: Skenderi,Salina;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0003-4779-4541 de Mont,Lisa;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0003-3829-0712 Toumazou,Maria;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: Ledderose,Julia;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0001-5458-6287 Colomb,Julien;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0002-3127-5520 Sehara,Keisuke;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0003-4368-8143 Brecht,Michael;Bernstein Center for Computational Neuroscience, House 6, Philippstr. 13, Humboldt Universität, Berlin, 10115 Germany. NeuroCure Cluster, Charité - Universitätsmedizin Berlin, D-10117 Berlin, Germany.;ORCID: 0000-0002-5387-0953 Naud,Richard;University of Ottawa Brain and Mind Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, K1H 8M5, Canada. Department of Physics, University of Ottawa, Ottawa, ON K1N 6N5, Canada;ORCID: 0000-0001-7383-3095 Larkum,Matthew E.;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0001-9799-2656 |
| Description | This repository contains behavioral, electrophysiological, functional imaging (two-photon imaging) and anatomical data that support our findings on the functional role of perirhinal input to neocortical layer 1 on learning. |
| License | Creative Commons Attribution 4.0 International Public License (https://creativecommons.org/licenses/by/4.0/) |
| References |
Perirhinal input to neocortical layer 1 controls learning [doi:10.1126/science.aaz3136] (IsSupplementTo)
|
| Funding |
DFG, LA 3442/2-1
DFG, EXC 257 NeuroCure DFG, DFG.327654276 (SFB 1315) EU, EU, EU.720270 (HBP SGA1) EU, EU.785907 (HBP SGA2) EU, EU.945539 (HBP SGA3) EU, EU.670118 (Active Cortex) Einstein Stiftung, EVF-2017-363 EMBO, ALTF 75-2014 NSERC, RGPIN-2017-06872 CIHR, RN383647–418955 |
| Keywords |
Systems Neuroscience
Electrophysiology Behavior Learning and memory Neocortex Primary somatosensory cortex (S1) Dendrites L5 pyramidal neuron Perirhinal cortex Layer 1 |
| Resource Type |
Dataset |