Calcium responses of perirhinal axons in layer 1 of S1 to microstimulation before and after the first training session. Pooled trials from all animals (n=3). 5-sec recording at 30 Hz, and stimulation occurred at 2 seconds.
Entry | Description |
---|---|
prePSTCa |
Axonal calcium responses (∆F/F) to microstimualtion before the training. |
postPSTCa |
Axonal calcium responses (∆F/F) to microstimualtion after the training. |
rewardPSTCa |
Axonal calcium responses (∆F/F) responses to reward alone. |
Excitatory postsynaptic currents (EPSCs) of S1 neurons in response to optogenetic activation of perirhinal axons in layer 1 of S1. See Fig. S4 for individual cell responses.
Entry | Description |
---|---|
preCNO |
EPSCs before CNO application |
postCNO |
EPSCs after CNO application |
Distribution of PRh projection in S1. Normalized signal distribution was measured along the neocortical depths.
For each file, the entry *Depth
represents the binned absolute depths of the neocortex. The entry norm_*
contains the normalized signals in the bins, where each column corresponds to the data from a brain section.
File name | Description |
---|---|
ChicagoBlue.mat | Intensity of ChicagoBlue in S1 after injection in mouse S1. |
MouseYFP.mat | Intensity of YFP (axon terminals) after injection of rAAV was in mouse PRh. |
RatYFP.mat | Intensity of YFP (axon terminals) after injection of rAAV was in rat PRh. |
Effects of DREADD inhibition of PRh inputs to L1 of S1 on learning of the microstimulation detection task.
Condition | Description |
---|---|
Untrained | Animals without any prior experience of pairing. No virus was expressed. No drug injection was performed. |
Ctrl | Animals after pairing sessions. No virus expression, but CNO was injected into L1 of S1. |
Dreadd | Animals after pairing sessions. Virus was expressed in PRh, and CNO was injected into L1 of S1 before testing of the learning. |
Expert_preCNO | Animals being fully trained with the task. Virus was expressed in PRh. Data was obtained before injection of CNO into L1 of S1. |
Expert_postCNO | Animals being fully trained with the task. Virus was expressed in PRh. Data was obtained after injection of CNO into L1 of S1. |
Entry | Description |
---|---|
<cond>_cumvals |
The cumulative learning curve statistics for the condition. Values on row N (N=1, ... 100) represents the cumulative learning score of each animal after N trials. |
<cond> |
The normalized learning scores for each animal belonging to the condition. |