# Metadata for DOI registration according to DataCite Metadata Schema 4.1. # For detailed schema description see https://doi.org/10.5438/0014 ## Required fields # The main researchers involved. Include digital identifier (e.g., ORCID) # if possible, including the prefix to indicate its type. authors: - firstname: Aref lastname: Kalantari affiliation: 'University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Neurology, Cologne, Germany' id: 'ORCID:0000-0003-3050-0930' - firstname: Carolin lastname: Hambrock affiliation: 'University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Neurology, Cologne, Germany' id: 'ORCID:0009-0009-0815-3996' - firstname: Christian lastname: Grefkes affiliation: 'Goethe University Frankfurt, University Hospital, Department of Neurology, Frankfurt am Main, Germany' id: 'ORCID:0000-0002-1656-720X' - firstname: Gereon lastname: Fink affiliation: 'University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Neurology, Cologne, Germany' id: 'ORCID:0000-0002-8230-1856' - firstname: Markus lastname: Aswendt affiliation: 'University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Neurology, Cologne, Germany' id: 'ORCID:0000-0003-1423-0934' # A title to describe the published resource. title: "Proportional recovery in mice with cortical stroke" # Additional information about the resource, e.g., a brief abstract. description: "In this dataset, we share the MRI and behavioral data relevant to our study investigating stroke recovery in 125 adult male C57Bl/6J mice with photothrombotic strokes in the sensorimotor cortex. Lesion size and location were determined during the first week post-stroke using in vivo T2-weighted MRI, and motor recovery was evaluated repeatedly over four weeks using the cylinder, grid walk, and rotating beam tests. These data were analyzed to explore whether the Proportional Recovery Rule (PRR), frequently used to predict motor recovery in acute stroke patients, applies to preclinical models of stroke recovery. Our findings revealed two distinct recovery patterns, resulting in the formulation of the Mouse Recovery Rule (MRR), which we compared against the traditional PRR. This dataset includes both MRI and behavioral data that were crucial for these analyses and provides a comprehensive resource for researchers aiming to investigate stroke recovery trajectories in animal models. In accordance with the FAIR (Findable, Accessible, Interoperable, and Reusable) principles, this dataset is made available to facilitate further research, ensure reproducibility, and promote the integration of these findings into preclinical and translational stroke research." # List of keywords the resource should be associated with. # Give as many keywords as possible, to make the resource findable. keywords: - motor deficit - mouse model - ischemic brain lesion - lesion size - behavior test - MRI # License information for this resource. Please provide the license name and/or a link to the license. # Please add also a corresponding LICENSE file to the repository. license: name: "CC BY-NC-SA 4.0" url: "https://creativecommons.org/licenses/by-nc-sa/4.0/" # Funding information for this resource. # Separate funder name and grant number by semicolon. # Funding information for this resource. # Separate funder name and grant number by semicolon. funding: - "DFG; 431549029 – SFB 1451" - "Friebe Foundation; T0498/28960/16" references: - id: "doi:tba" reftype: "IsSupplementTo" citation: "Kalantari, Aref et. al 2024, Proportional recovery in mice with cortical stroke, STROKE, first submission on XX.10.2024" # Resource type. Default is Dataset, other possible values are Software, Image, Text. resourcetype: Dataset # Do not edit or remove the following line templateversion: 1.2