Human-L2-3-Cortical-Microcircuit/NeuroML2/channels/Kv3_1.channel.nml

<?xml version="1.0" encoding="ISO-8859-1"?>
<neuroml xmlns="http://www.neuroml.org/schema/neuroml2" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.neuroml.org/schema/neuroml2 https://raw.github.com/NeuroML/NeuroML2/development/Schemas/NeuroML2/NeuroML_v2beta4.xsd" id="Kv3_1">

    <notes>NeuroML file containing a single Channel description</notes>

    <ionChannel id="Kv3_1" conductance="10pS" type="ionChannelHH" species="k">

        <notes>Fast, non inactivating K+ current

Comment from original mod file:
:Reference : :		Characterization of a Shaw-related potassium channel family in rat brain, The EMBO Journal, vol.11, no.7,2473-2486 (1992)</notes>

        <annotation>
            <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                <rdf:Description rdf:about="Kv3_1">

                    <bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
                        <rdf:Bag>
                            <rdf:li>Models of Neocortical Layer 5b Pyramidal Cells Capturing a Wide Range of Dendritic and Perisomatic Active Properties,
            Etay Hay, Sean Hill, Felix Schürmann, Henry Markram and Idan Segev, PLoS Comp Biol 2011</rdf:li>
                            <rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/21829333"/>
                        </rdf:Bag>
                    </bqmodel:isDescribedBy>


                    <bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
                        <rdf:Bag>
                            <rdf:li>K channels</rdf:li>
                            <rdf:li rdf:resource="http://senselab.med.yale.edu/neurondb/channelGene2.aspx#table3"/>
                        </rdf:Bag>
                    </bqbiol:isVersionOf>

                </rdf:Description>
            </rdf:RDF>
        </annotation>

        <gate id="m" type="gateHHtauInf" instances="1">
            <timeCourse type="Kv3_1_m_tau_tau"/>
            <steadyState type="HHSigmoidVariable" rate="1" scale="9.7mV" midpoint="18.7mV"/>
        </gate>

    </ionChannel>

    <ComponentType name="Kv3_1_m_tau_tau" extends="baseVoltageDepTime">
        <Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
        <Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>

        <Dynamics>
            <DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
            <DerivedVariable name="t" exposure="t" dimension="time" value="(4/(1 + exp( (V+46.56) / (-44.140) ))) * TIME_SCALE"/>
        </Dynamics>

    </ComponentType>

</neuroml>