biophys_HL23PYR.hoc 2.8 KB

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  1. proc biophys_HL23PYR(){
  2. //$o1.delete_axon(3,1.75,1,1)
  3. forsec $o1.all {
  4. insert pas
  5. Ra = 100
  6. cm = 1
  7. e_pas = -80
  8. g_pas = 0.0000954
  9. insert Ih
  10. }
  11. forsec $o1.somatic {
  12. insert SK
  13. insert CaDynamics
  14. insert Ca_LVA
  15. insert Ca_HVA
  16. insert K_T
  17. insert K_P
  18. insert Kv3_1
  19. insert NaTg
  20. insert Im
  21. ek = -85
  22. ena = 50
  23. gamma_CaDynamics = 0.0005
  24. vshiftm_NaTg = 13
  25. vshifth_NaTg = 15
  26. slopem_NaTg = 7
  27. gbar_Ih = 0.000148
  28. }
  29. forsec $o1.apical {
  30. cm = 2
  31. }
  32. forsec $o1.basal {
  33. cm = 2
  34. gbar_Ih = 0.000000709
  35. }
  36. $o1.distribute_channels("apic","gbar_Ih",2,-0.8696,3.6161,0.0,2.0870,$o1.soma.gbar_Ih)
  37. forsec $o1.axonal {
  38. insert SK
  39. insert Ca_LVA
  40. insert Ca_HVA
  41. insert K_T
  42. insert K_P
  43. insert Nap
  44. insert Kv3_1
  45. insert NaTg
  46. insert CaDynamics
  47. insert Im
  48. ek = -85
  49. ena = 50
  50. vshifth_NaTg = 10
  51. slopem_NaTg = 9
  52. gamma_CaDynamics = 0.0005
  53. }
  54. $o1.distribute_channels("axon","decay_CaDynamics",0,1.000000,0.000000,0.000000,0.000000,226.0000000000)
  55. $o1.distribute_channels("axon","gbar_SK",0,1.000000,0.000000,0.000000,0.000000,0.0145000000)
  56. $o1.distribute_channels("axon","gbar_Ca_LVA",0,1.000000,0.000000,0.000000,0.000000,0.0439000000)
  57. $o1.distribute_channels("axon","gbar_Ca_HVA",0,1.000000,0.000000,0.000000,0.000000,0.0003060000)
  58. $o1.distribute_channels("axon","gbar_Kv3_1",0,1.000000,0.000000,0.000000,0.000000,0.9410000000)
  59. $o1.distribute_channels("axon","gbar_K_T",0,1.000000,0.000000,0.000000,0.000000,0.0424000000)
  60. $o1.distribute_channels("axon","gbar_K_P",0,1.000000,0.000000,0.000000,0.000000,0.3380000000)
  61. $o1.distribute_channels("axon","gbar_Nap",0,1.000000,0.000000,0.000000,0.000000,0.0084200000)
  62. $o1.distribute_channels("axon","gbar_NaTg",0,1.000000,0.000000,0.000000,0.000000,1.3800000000)
  63. $o1.distribute_channels("axon","gbar_Im",0,1.000000,0.000000,0.000000,0.000000,0.0000000000)
  64. $o1.distribute_channels("soma","decay_CaDynamics",0,1.000000,0.000000,0.000000,0.000000,20.0000000000)
  65. $o1.distribute_channels("soma","gbar_Im",0,1.000000,0.000000,0.000000,0.000000,0.0003060000)
  66. $o1.distribute_channels("soma","gbar_Ca_LVA",0,1.000000,0.000000,0.000000,0.000000,0.0029600000)
  67. $o1.distribute_channels("soma","gbar_Ca_HVA",0,1.000000,0.000000,0.000000,0.000000,0.0015500000)
  68. $o1.distribute_channels("soma","gbar_Kv3_1",0,1.000000,0.000000,0.000000,0.000000,0.0424000000)
  69. $o1.distribute_channels("soma","gbar_SK",0,1.000000,0.000000,0.000000,0.000000,0.0008530000)
  70. $o1.distribute_channels("soma","gbar_K_T",0,1.000000,0.000000,0.000000,0.000000,0.0605000000)
  71. $o1.distribute_channels("soma","gbar_K_P",0,1.000000,0.000000,0.000000,0.000000,0.0002080000)
  72. $o1.distribute_channels("soma","gbar_NaTg",0,1.000000,0.000000,0.000000,0.000000,0.2720000000)
  73. $o1.myelin{
  74. Ra = 100
  75. cm = 0.02
  76. }
  77. }