NeuroML conversions of the Yao et al 2022 Human L2/3 cortical microcircuit:

Yao, H. K. et al. Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits. Cell Rep. 38, (2022).



Non git-annex files can also be obtained from https://github.com/sanjayankur31/Human-L2-3-Cortical-Microcircuit/

Ankur Sinha (Ankur Sinha Gmail) dd815fcd77 chore(nml): update script to delete all nsg jobs 10 mēneši atpakaļ
.github 25062dd353 ci(annex): remove all annex bits 1 gadu atpakaļ
L23Net dda6aba361 feat(neuroml): conversion of ProbUDF synapse also complete 1 gadu atpakaļ
NeuroML2 dd815fcd77 chore(nml): update script to delete all nsg jobs 10 mēneši atpakaļ
.flake8 4b296b81fb chore: add flake config 2 gadi atpakaļ
.gitignore e0f831ae0b chore: do not track temporary cell files 1 gadu atpakaļ
README.md 4b970fb588 Add files via upload 2 gadi atpakaļ
lfpy_env.yml 07d31ccf51 Add files via upload 2 gadi atpakaļ

README.md

Human L2/3 Cortical Circuit Model --- Yao-et-al.-2022

============================================================================== Author: Heng Kang yao

This is the readme for the model associated with the paper:

Yao, H. K. et al. Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits. Cell Rep. 38, (2022).

Network Simulations: Simulation code associated with the default L2/3 circuit used throughout the manuscript is in the /L23Net directory.

To run simulations, install all of the necessary python modules (see lfpy_env.yml), compile the mod files within the mod folder, and submit the simulations in parallel. To run the depression condition, set MDD to True.

To run the circuit in parallel, use the following command:

mpiexec -n 400 python circuit.py 1234

The 400 corresponds to the number of CPU and 1234 correspond to the seed.