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- :Comment :
- :Reference : : Kole,Hallermann,and Stuart, J. Neurosci. 2006
- NEURON {
- SUFFIX Ih
- NONSPECIFIC_CURRENT ihcn
- RANGE gbar, g, ihcn, shift1, shift2, shift3, shift4, shift5, shift6
- }
- UNITS {
- (S) = (siemens)
- (mV) = (millivolt)
- (mA) = (milliamp)
- }
- PARAMETER {
- gbar = 0.00001 (S/cm2)
- ehcn = -45.0 (mV)
- shift1 = 154.9
- shift2 = 11.9
- shift3 = 0
- shift4 = 33.1
- shift5 = 6.43
- shift6 = 193
- }
- ASSIGNED {
- v (mV)
- ihcn (mA/cm2)
- g (S/cm2)
- mInf
- mTau
- mAlpha
- mBeta
- }
- STATE {
- m
- }
- BREAKPOINT {
- SOLVE states METHOD cnexp
- g = gbar*m
- ihcn = g*(v-ehcn)
- }
- DERIVATIVE states {
- rates()
- m' = (mInf-m)/mTau
- }
- INITIAL{
- rates()
- m = mInf
- }
- PROCEDURE rates(){
- UNITSOFF
- if(v == -shift1){
- v = v + 0.0001
- }
- if(shift4 == 0){
- shift4 = shift4 + 0.0001
- }
- if(shift2 == 0){
- shift2 = shift2 + 0.0001
- }
- mAlpha = 0.001*(shift5)*(v+shift1)/(exp((v+shift1)/(shift2))-1)
- mBeta = 0.001*(shift6)*exp((v+shift3)/(shift4))
- mInf = mAlpha/(mAlpha + mBeta)
- mTau = 1/(mAlpha + mBeta)
- UNITSON
- }
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