:Comment : :Reference : : Kole,Hallermann,and Stuart, J. Neurosci. 2006 NEURON { SUFFIX Ih NONSPECIFIC_CURRENT ihcn RANGE gbar, g, ihcn, shift1, shift2, shift3, shift4, shift5, shift6 } UNITS { (S) = (siemens) (mV) = (millivolt) (mA) = (milliamp) } PARAMETER { gbar = 0.00001 (S/cm2) ehcn = -45.0 (mV) shift1 = 154.9 shift2 = 11.9 shift3 = 0 shift4 = 33.1 shift5 = 6.43 shift6 = 193 } ASSIGNED { v (mV) ihcn (mA/cm2) g (S/cm2) mInf mTau mAlpha mBeta } STATE { m } BREAKPOINT { SOLVE states METHOD cnexp g = gbar*m ihcn = g*(v-ehcn) } DERIVATIVE states { rates() m' = (mInf-m)/mTau } INITIAL{ rates() m = mInf } PROCEDURE rates(){ UNITSOFF if(v == -shift1){ v = v + 0.0001 } if(shift4 == 0){ shift4 = shift4 + 0.0001 } if(shift2 == 0){ shift2 = shift2 + 0.0001 } mAlpha = 0.001*(shift5)*(v+shift1)/(exp((v+shift1)/(shift2))-1) mBeta = 0.001*(shift6)*exp((v+shift3)/(shift4)) mInf = mAlpha/(mAlpha + mBeta) mTau = 1/(mAlpha + mBeta) UNITSON }