{"text_format":"2","workbook":"xlsx","n_sheets":7,"sheets":["Figure 1","Figure 2","Figure 3","Figure 4","Figure 5","Figure 6","Figure S1"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Figure 1","index":0,"n_rows":17,"n_cols":42,"rows_kept":17,"cut":false,"hidden":false,"merged":[]}
[]
[null,"FIGURE 1B",null,null,null,"FIGURE 1D",null,null,null,"FIGURE 1F",null,null,null,"FIGURE 1G",{"$nulls":26},"FIGURE 1I"]
[]
["GFAP/tubulin","naive","MCAO",null,"ATX/ß-actin","naive","MCAO",null,"infarct volume (mm3)","WT","ATXfl/fl GFAP-Cre+ ",null,"mNSS","timepoint [h]","WT",{"$nulls":11},"ATXfl/fl GFAP-Cre+ ",{"$nulls":12},"Casp3+ cells/mm2","WT","ATXfl/fl GFAP-Cre+ "]
[]
[null,0.30702600000000002,0.52285999999999999,null,null,0.59009500000000004,0.656779,null,null,5.3908800000000001,15.932639999999999,null,null,3,7,10,8,13,13,10,9,4,13,11,13,10,13,4,3,13,6,8,13,5,4,9,12,11,null,null,1.4804260499999999,1.3057357700000001]
[null,0.25691399999999998,0.42058200000000001,null,null,0.215921,0.46695599999999998,null,null,16.589759999999998,8.0438399999999994,null,null,24,10,8,4,4,12,6,8,3,11,12,13,11,11,3,3,10,10,5,5,5,4,6,9,9,null,null,0.65939135000000004,0.88252781999999996]
[null,0.26232499999999997,0.56420599999999999,null,null,0.37443100000000001,0.35772900000000002,null,null,27.36768,10.256880000000001,null,null,48,5,12,1,6,12,3,13,1,7,8,13,13,8,4,3,3,4,4,4,5,3,10,8,7,null,null,2.2833370400000002,2.3978607599999999]
[null,0.27480300000000002,0.53533200000000003,null,null,0.42043900000000001,0.50230799999999998,null,null,57.607680000000002,3.1644000000000001,null,null,72,5,10,1,5,7,3,9,1,7,8,8,13,11,4,3,3,4,4,4,5,4,9,8,6,null,null,4.8816960399999996,0.45599115000000001]
[null,0.28248299999999998,0.57856600000000002,null,null,0.28705000000000003,0.86058900000000005,null,null,12.972479999999999,1.6732800000000001,{"$nulls":29},2.4170643200000002,0.10653372999999999]
[{"$nulls":6},0.72553599999999996,null,null,23.096640000000001,7.95024,{"$nulls":29},1.6012682600000001,1.2757873799999999]
[{"$nulls":9},12.278879999999999,1.09632,{"$nulls":30},0.42692169000000002]
[{"$nulls":9},58.736879999999999,4.2794400000000001,{"$nulls":30},0.67768896000000001]
[{"$nulls":9},31.394880000000001,19.1448]
[{"$nulls":9},47.72784]
[{"$nulls":9},19.590720000000001]
[{"$nulls":9},27.447600000000001]

{"sheet":"Figure 2","index":1,"n_rows":52,"n_cols":29,"rows_kept":52,"cut":false,"hidden":false,"merged":[]}
[]
[null,"FIGURE 2A",{"$nulls":5},"FIGURE 2B",{"$nulls":5},"FIGURE 2C",null,null,null,"FIGURE 2D",null,null,null,"FIGURE 2E",null,null,null,"FIGURE 2F"]
[]
["ATX CSF (ng/ml)","C","1d stroke","2-7d stroke",">7-14d stroke",null,"ATX serum (ng/ml)","C","1d stroke","2-7d stroke",">7-14d stroke",null,null,"ΔNIHSSadm-24h","ATX CSF",null,"ATX CSF (ng/ml)","ΔNIHSS6h-24h↓","ΔNIHSS6h-24h↑",null,null,"Mimatch_ml","CSF_ATX",null,"CSF concentrations (ng/ml)","LPA",null,"LPC"]
[{"$nulls":25},"C","Stroke","C","Stroke"]
[null,235.58,435.402672,291.58178800000002,358.50716399999999,null,null,213.24499599999999,297.64999999999998,241.1,299.41165599999999,null,null,-2,476.77582200000001,null,null,476.77582200000001,331.193736,null,null,6.4,291.58,null,null,22.943000000000001,9.827,2.8679999999999999,0.32300000000000001]
[null,223.25,311.67132900000001,333.37282900000002,370.86536000000001,null,null,187.94470200000001,355.93,227.95,329.80471499999999,null,null,-2,584.357935,null,null,584.357935,386.68626599999999,null,null,8.98,300.20999999999998,null,null,8.11,28.161000000000001,0.109,11.55]
[null,307.25,476.77582200000001,362.02956799999998,321.76090099999999,null,null,400.57629500000002,373.25,206.79,179.56006199999999,null,null,0,435.402672,null,null,435.402672,333.37282900000002,null,null,22.47,318.57,null,null,11.8,16.597999999999999,1.972,2.7810000000000001]
[null,284.54000000000002,367.25342499999999,318.56687499999998,null,null,null,378.62141800000001,296.05,278.89999999999998,79.5600594,null,null,0,370.86536000000001,null,null,370.86536000000001,362.02956799999998,null,null,45.3,362.03,null,null,4.2759999999999998,10.227,0.32300000000000001,26.036999999999999]
[null,193.1,584.357935,366.38776999999999,null,null,null,309.48605700000002,319.92,200.61,226.24500499999999,null,null,0,364.71611799999999,null,null,364.71611799999999,319.34299900000002,null,null,35.28,366.39,null,null,10.3,19.375,0.46500000000000002,1.873]
[null,275.88,364.71611799999999,319.34299900000002,null,null,null,352.64395400000001,378.64,251.31,null,null,null,0,338.50715500000001,null,null,338.50715500000001,366.3877,null,null,19.329999999999998,367.25,null,null,27.202999999999999,17.292000000000002,4.5220000000000002,3.411]
[null,322.45,null,338.50715500000001,null,null,null,307.831928,599.17999999999995,248.74,null,null,null,0,367.25342499999999,null,null,367.25342499999999,266.35792099999998,null,null,62.9,386.69,null,null,7.7210000000000001,18.495000000000001,8.3019999999999996,4.03]
[null,378.06,null,300.208662,null,null,null,477.98229300000003,302.55,380.19,null,null,null,0,358.50716399999999,null,null,358.50716399999999,291.58178800000002,{"$nulls":6},14.852,9.7439999999999998,1.3520000000000001,8.17]
[null,273.88,null,266.35792099999998,null,null,null,304.16166199999998,400.37,142.1,null,null,null,1,331.193736,null,null,null,318.56687499999998,{"$nulls":6},19.826000000000001,14.238,4.516,3.8809999999999998]
[null,388.72,null,327.99969199999998,null,null,null,252.794321,341.07,216.75,null,null,null,1,386.68626599999999,null,null,null,300.208662,{"$nulls":6},10.492000000000001,20.594000000000001,6.0119999999999996,6.5670000000000002]
[null,228.03,null,386.68626599999999,null,null,null,284.33568700000001,518.97,134.05000000000001,null,null,null,1,333.37282900000002,null,null,null,311.67132900000001,{"$nulls":6},13.576000000000001,24.884,4.2450000000000001,8.2230000000000008]
[null,443.52,null,331.193736,null,null,null,340.98981199999997,128.93,185.29,null,null,null,1,362.02956799999998,{"$nulls":10},14.101000000000001,9.8719999999999999,3.3730000000000002,14.172000000000001]
[null,392.12,{"$nulls":5},325.61999300000002,236.38,438.93,null,null,null,1,319.34299900000002,{"$nulls":10},9.6940000000000008,13.125999999999999,9.0190000000000001,3.8260000000000001]
[null,355.7,{"$nulls":5},213.161674,256.70999999999998,182.1,null,null,null,2,366.3877,{"$nulls":10},8.1709999999999994,11.353999999999999,9.3699999999999992,4.702]
[null,294.89999999999998,{"$nulls":5},303.370001,380.45,194.07,null,null,null,2,266.35792099999998,{"$nulls":10},3.7029999999999998,11.106,5.2210000000000001,5.4160000000000004]
[null,338.36,{"$nulls":5},269.36999700000001,144.44,196.12,null,null,null,2,291.58178800000002,{"$nulls":10},5.4340000000000002,8.8789999999999996,9.4930000000000003,8.6750000000000007]
[null,274.24,{"$nulls":5},278.57833099999999,196.34,243.76,null,null,null,4,318.56687499999998,{"$nulls":10},12.125999999999999,12.515000000000001,1.585,9.1929999999999996]
[null,239.25,{"$nulls":5},252.161664,153.5,220.48,null,null,null,5,300.208662,{"$nulls":10},27.491,26.388999999999999,3.089,18.734000000000002]
[null,293.16000000000003,{"$nulls":5},209.28667100000001,164.9,174.57,null,null,null,6,311.67132900000001,{"$nulls":11},7.3540000000000001,7.0819999999999999,35.222000000000001]
[null,337.73,{"$nulls":5},211.177786,258.39999999999998,259.13,{"$nulls":16},16.076000000000001,19.013999999999999,15.353]
[{"$nulls":7},219.578338,425.39,260.94,{"$nulls":17},17.324999999999999,30.864000000000001]
[{"$nulls":7},270.65147999999999,118.52,223.3]
[{"$nulls":7},196.370003,257.27999999999997,236.15]
[{"$nulls":7},176.065009,251.21,152.43]
[{"$nulls":7},171.40334899999999,251.89,192.536666]
[{"$nulls":7},186.89207500000001,237.49,168.48972499999999]
[{"$nulls":7},140.61388099999999,358.7,221.50194500000001]
[{"$nulls":7},275.03665999999998,207,250.04996399999999]
[{"$nulls":7},265.53667300000001,338.53,194.80470600000001]
[{"$nulls":7},244.578326,317.58,321.779291]
[{"$nulls":8},425.38,64.437732100000005]
[{"$nulls":8},455.73,240.41632200000001]
[{"$nulls":8},299.49]
[{"$nulls":8},212.93]
[{"$nulls":8},233.8]
[{"$nulls":8},443.03]
[{"$nulls":8},351.81]
[{"$nulls":8},205.38]
[{"$nulls":8},293.10000000000002]
[{"$nulls":8},182.22]
[{"$nulls":8},148.78]
[{"$nulls":8},317.27]
[{"$nulls":8},303.95]
[{"$nulls":8},190.36]
[{"$nulls":8},214.34]
[{"$nulls":8},135.58000000000001]
[{"$nulls":8},291.88422200000002]

{"sheet":"Figure 3","index":2,"n_rows":34,"n_cols":35,"rows_kept":34,"cut":false,"hidden":false,"merged":[]}
[]
[null,null,"FIGURE 3C",null,null,null,"FIGURE 3D",{"$nulls":25},"FIGURE 3E"]
[]
[null,"infarct volume (mm3)","vehicle","PF8380",null,"mNSS","timepoint [h]","vehicle",{"$nulls":10},"PF8380",{"$nulls":12},"LPA-CSF amounts ","C","MCAO"]
[{"$nulls":31},"normalized peak area (a.u.)",null,"vehicle","PF8380"]
[null,null,21.554639999999999,33.903359999999999,null,null,3,7,9,6,14,8,7,13,5,10,12,13,12,10,14,8,10,9,4,11,4,8,6,13,null,null,1.3723444E-2,3.6422769000000001E-2,1.9328649999999999E-2]
[null,null,38.638800000000003,47.387999999999998,null,null,24,7,8,9,14,11,8,12,5,11,8,12,10,6,13,9,12,8,5,7,3,5,5,6,null,null,4.3879318E-2,0.103521061,2.9137046999999999E-2]
[null,null,13.743600000000001,9.1017600000000005,null,null,48,8,8,6,14,8,11,9,5,12,7,13,9,3,6,7,9,7,4,8,3,4,5,7,null,null,1.9416851999999998E-2,0.12542333,3.8989620000000002E-3]
[null,null,40.787280000000003,1.33416,null,null,72,6,7,7,14,8,10,8,4,9,7,13,8,3,6,6,11,7,3,6,3,4,5,5,null,null,5.9673792000000003E-2,6.7899851999999997E-2,1.7213230000000001E-3]
[null,null,44.150399999999998,1.1042400000000001,{"$nulls":28},4.6867757000000003E-2,9.9558712999999993E-2,1.9361469999999999E-2]
[null,null,21.250319999999999,37.18224,{"$nulls":28},5.2391817E-2,0.10751796499999999]
[null,null,48.304560000000002,25.250640000000001,{"$nulls":28},8.4452898999999998E-2,2.4106675000000001E-2]
[null,null,61.086959999999998,3.89256,{"$nulls":28},5.8360308E-2,9.1789661999999994E-2]
[null,null,18.004079999999998,17.09808,{"$nulls":28},1.9567197000000001E-2,0.119234515]
[null,null,36.826560000000001,39.630000000000003,{"$nulls":28},1.6375872999999999E-2,6.9765388999999997E-2]
[null,null,37.187759999999997,19.266960000000001,{"$nulls":28},0.103458076]
[null,null,null,13.670640000000001,{"$nulls":28},9.1912364999999996E-2]
[]
[]
[null,null,"FIGURE 3G"]
[]
[null,"Casp3+ cells/mm2","vehicle","PF8380"]
[]
[null,null,0.84503983000000005,0.55200017999999995]
[null,null,3.8058759499999999,8.4755365900000008]
[null,null,14.5878841,3.0216855800000002]
[null,null,1.4576174500000001,6.1138531599999997]
[null,null,3.2397177199999998,1.58200165]
[null,null,7.4760962299999996,0.74040384999999997]
[null,null,21.368796100000001,6.0539440799999999]
[null,null,3.27337582,5.5120514610000004]
[null,null,14.100284800000001,6.4681112499999998]
[null,null,10.4654408,1.3347669200000001]
[null,null,null,5.6507575599999997]

{"sheet":"Figure 4","index":3,"n_rows":34,"n_cols":39,"rows_kept":34,"cut":false,"hidden":false,"merged":[]}
[]
[]
[null,"FIGURE 4B",{"$nulls":5},"FIGURE 4D",null,null,null,"FIGURE 4E"]
["sEPSC","frequency (Hz)",null,"amplitude (pA)",null,null,"infarct volume (mm3)","WT","PRG-1R346T",null,"mNSS","timepoint [h]","vehicle",{"$nulls":11},"PF8380"]
[null,"WT","PRG-1R346T","WT","PRG-1R346T"]
[null,0.81365969999999999,1.235714,18.406089999999999,17.082740000000001,null,null,13.47,11.95,null,null,3,8,11,5,1,5,7,4,3,3,6,5,6,13,8,4,8,4,12,7,10,9,5,8,8]
[null,0.77534479999999995,1.264176,14.763669999999999,21.40822,null,null,17.48,23.36,null,null,24,6,6,3,null,4,3,3,3,3,2,4,4,12,6,4,11,3,5,5,12,11,4,4,5]
[null,0.63449049999999996,1.23047,14.68014,16.55847,null,null,9.2899999999999991,24.02]
[null,1.175106,0.95137609999999995,18.18111,19.618929999999999,null,null,10.29,11.41]
[null,1.1277779999999999,1.02844,18.799800000000001,20.040330000000001,null,null,5.83,15.67]
[null,0.91056910000000002,0.95536330000000003,18.885400000000001,15.04881,null,null,11.36,15.57]
[null,0.87281260000000005,1.537512,17.865500000000001,28.11787,null,null,15.92,23.65]
[null,1.137057,1.8857919999999999,16.54177,16.030059999999999,null,null,14.59,41.45]
[null,0.63555130000000004,0.80860010000000004,16.762440000000002,13.93637,null,null,9.41,37.26]
[null,0.89187720000000004,1.241258,15.09388,20.436170000000001,null,null,13.91,22.57]
[{"$nulls":7},2.4775200000000002,19.88]
[{"$nulls":7},15.8772]
[]
[]
[null,"FIGURE 4G",{"$nulls":5},"FIGURE 4H",null,null,null,"FIGURE 4J",null,null,null,"FIGURE 4K"]
[]
["Casp3+ cells/mm2","WT","PRG-1R346T",null,null,null,"NfL (pg/L)","WT","PRG-1R346T",null,"infarct volume (mm3)","WT","PRG-1-/-/LPA2-/- ",null,"mNSS","timepoint [h]","WT",{"$nulls":11},"PF8380"]
[]
[null,1.1499999999999999,2.37,{"$nulls":4},2217.67,14537.14,null,null,13.58112,9.9551999999999996,null,null,3,13,8,3,4,8,11,7,6,8,9,12,14,7,12,11,11,12,8,8,12,7,6,5]
[null,0.94,4.47,{"$nulls":4},733.73,5023.2,null,null,6.7099200000000003,12.88992,null,null,24,10,5,3,3,8,9,6,4,7,7,7,13,5,12,8,8,10,5,8,12,8,6,4]
[null,0.85,15.24,{"$nulls":4},1089.06,30966.880000000001,null,null,7.3826400000000003,11.38968,null,null,48,5,3,4,3,8,7,5,3,4,5,7,14,4,13,6,8,9,7,8,6,11,5,2]
[null,1.58,1.43,{"$nulls":4},1036.23,2504.33,null,null,48.13344,13.74672,null,null,72,5,4,3,3,8,6,6,3,5,5,6,14,4,14,5,8,6,6,8,6,10,5,2]
[null,0.84,2.2999999999999998,{"$nulls":4},4088.59,20381.400000000001,null,null,4.5472799999999998,8.0042399999999994]
[null,0.25,0.54,{"$nulls":4},4969.3900000000003,24350.799999999999,null,null,9.2652000000000001,11.8056]
[null,5.4,9.51,{"$nulls":5},22219.52,null,null,7.9483199999999998,21.373200000000001]
[null,2.57,14.92,{"$nulls":5},975,null,null,28.081679999999999,39.433920000000001]
[null,0.95,4.43,{"$nulls":8},5.8490399999999996,42.172080000000001]
[{"$nulls":11},51.12144,51.499920000000003]
[{"$nulls":11},2.06616,1.86504]

{"sheet":"Figure 5","index":4,"n_rows":112,"n_cols":47,"rows_kept":112,"cut":false,"hidden":false,"merged":[]}
[]
[null,"FIGURE 5C",{"$nulls":5},"FIGURE 5D",{"$nulls":4},"FIGURE 5E"]
[]
["penumbra volume (mm3)","penumbra 24h ",{"$nulls":4},"infarct volume (mm3)","penumbra 72h ",null,null,null,"mNSS","timepoint [h]","WT",{"$nulls":15},"WT + PF8380"]
[null,"WT","WT PF8380","PRG-1R346T","PRG-1R346T PF8380",null,null,"WT","WT PF8380","PRG-1R346T","PRG-1R346T PF8380"]
[null,35.079084199999997,19.530385800000001,44.831884500000001,19.676490260000001,null,null,27.2208553,15.2849822,39.411855600000003,16.71761283,null,3,5,3,6,10,9,5,8,10,12,14,9,5,13,null,null,null,3,5,7,2,3,5,3,10,7,12,4,9,6,6,7,4]
[null,46.171903200000003,20.677452200000001,44.617071199999998,30.6282842,null,null,28.586879100000001,17.968815200000002,39.143338999999997,21.657355249999998,null,24,7,3,1,6,2,6,6,11,12,14,12,4,11,null,null,null,3,3,3,3,3,5,3,8,5,13,3,6,null,3,4,1,2,4]
[null,19.826241799999998,25.962454699999999,37.068410399999998,26.640058639999999,null,null,16.904802199999999,22.075068399999999,29.707512999999999,20.422073300000001,null,48,6,3,0,1,2,7,4,9,10,12,13,3,7,null,null,null,3,3,3,3,2,5,3,13,3,12,3,6,4,1,4,3,2,2]
[null,34.262910300000001,25.021508300000001,39.106887499999999,29.97833941,null,null,28.700637799999999,22.148885400000001,36.005609399999997,22.09492427,null,72,6,3,4,1,1,6,3,12,12,11,11,2,8,null,null,null,1,1,2,3,4,5,1,13,3,11,3,5,3,1,5,2,2,2]
[null,28.890711,19.5633047,33.572581399999997,28.548325590000001,null,null,24.485388700000001,14.0761308,22.837726799999999,19.05740699]
[null,23.4728849,{"$nulls":5},16.463106100000001]
[]
["penumbra volume (mm3)","stroke 24h ",{"$nulls":4},"infarct volume (mm3)","stroke 72h ",null,null,null,"mNSS","timepoint [h]","PRG-1R346T",{"$nulls":15},"PRG-1R346T PF8380"]
[null,"WT","WT PF8380","PRG-1R346T","PRG-1R346T PF8380",null,null,"WT","WT PF8380","PRG-1R346T","PRG-1R346T PF8380"]
[null,62.697710600000001,38.825964399999997,87.0797113,41.691225699999997,null,null,54.44171,30.569959999999998,78.823710000000005,33.435229999999997,null,3,8,11,7,11,11,4,5,13,10,3,6,8,13,null,9,11,3,13,5,10,6,3,1,3,12,9,8,8,5,null,4]
[null,65.429758100000001,44.193630400000004,86.542677900000001,51.570710499999997,null,null,57.173760000000001,35.937629999999999,78.286670000000001,43.314709999999998,null,24,4,11,4,4,8,2,3,14,11,1,4,5,10,1,10,11,2,8,4,6,4,3,1,1,13,11,9,9,5,10,4]
[null,42.065604499999999,52.406136699999998,67.671025999999998,49.100146600000002,null,null,33.809609999999999,44.15014,59.415030000000002,40.844149999999999,null,48,5,13,3,4,8,4,2,12,9,2,4,6,8,1,null,null,1,10,3,5,5,3,1,1,14,8,5,4,4,4]
[null,65.6572757,52.553770700000001,80.267218799999995,52.445848499999997,null,null,57.40128,44.29777,72.011219999999994,44.18985,null,72,5,11,3,3,7,3,3,9,8,2,6,5,8,1,12,7,1,9,3,6,3,2,1,3,11,10,4,1,3,4,2]
[null,57.226777400000003,36.408261600000003,53.931453599999998,46.370814000000003,null,null,48.970779999999998,28.152259999999998,45.675449999999998,38.114809999999999]
[null,41.182212200000002,{"$nulls":5},32.926209999999998]
[]
[]
[null,"FIGURE 5F"]
[]
["latency (s)","timepoint [h]","WT",{"$nulls":4},"WT + PF8380"]
[]
[null,3,16,105,60,16,102,55,70,132,177,108.5]
[null,24,14,30,97,111,8,97,71,150,170,219]
[null,48,51,77,157,121,101,96,167,107,265,249]
[null,72,94,264,242,112,178,131,350,127,251,215]
[]
[]
[]
["latency (s)","timepoint [h]","PRG-1R346T",{"$nulls":4},"PRG-1R346T PF8380"]
[]
[null,3,16,105,60,16,102,55,70,132,177,108.5]
[null,24,14,30,97,111,8,97,71,150,170,219]
[null,48,51,77,157,121,101,96,167,107,265,249]
[null,72,94,264,242,112,178,131,350,127,251,215]
[]
[]
[null,"FIGURE 5H",null,null,"FIGURE 5I",null,null,"FIGURE 5J"]
[]
[null,"C","MCAO",null,"before\nPF8380","after\nPF8380",null,"C","MCAO","MCAO + PF8380"]
["sEPSC","frequency (Hz)",null,"sEPSC frequency in % of value before PF8380",null,null,null,"amplitude (pA)"]
[null,540597,4.0303000000000004,null,100,61.365158899999997,null,7.7259099999999998,7.2104699999999999,6.7277300000000002]
[null,13.3429,20.5564,null,100,85.639022400000002,null,9.9852699999999999,12.154400000000001,13.1142]
[null,10.105700000000001,10.586600000000001,null,100,55.602932000000003,null,10.6294,9.6204099999999997,12.551600000000001]
[null,6.2241600000000004,43.945700000000002,null,100,94.800173900000004,null,9.0608900000000006,20.4938,19.841999999999999]
[null,22.113800000000001,13.6912,null,100,65.577743400000003,null,15.0618,9.4495100000000001,9.2131000000000007]
[null,4.7563599999999999,{"$nulls":5},13.1333]
[null,1.3030299999999999,{"$nulls":5},7.3806900000000004]
[null,30.849699999999999]
{"$rows_empty":8}
[null,"FIGURE 5K",{"$nulls":5},"FIGURE 5L"]
[]
["firing rate (Hz) ","L4 C","L4 MCAO","L5 C","L5 MCAO",null,"firing rate (Hz) ","L4","L4 + PF8380","L5","L5 + PF8380"]
[{"$nulls":7},"WT MCAO",null,"WT MCAO"]
[null,13,16,16,21,null,null,9.0757955179999996,7.8085879599999997,13.141991340000001,7.0784511200000004]
[null,13,18,16,21,null,null,8.7744879309999995,8.9092825809999994,12.842185089999999,10.76543985]
[null,15,18,16,18,null,null,8.2565951599999998,7.2063309279999999,12.539737199999999,9.5247759389999995]
[null,11,18,17,20,null,null,9.7014972700000008,5.1752271070000004,12.3818521,10.6105512]
[null,14,17,17,19,null,null,null,7.3285950800000004,null,10.805504000000001]
[null,14,15,16,23]
[null,12,15,18,20]
[null,null,19,null,21]
[null,null,15,null,19,null,"firing rate (Hz) ","L4","L4 + PF8380","L5","L5 + PF8380"]
[null,null,19,null,22,null,null,"PRG-1R346T MCAO",null,"PRG-1R346T MCAO"]
[{"$nulls":7},9.0048390299999994,6.3020666900000002,11.3784949,7.9696315799999997]
[{"$nulls":7},10.267651280000001,6.0618569830000002,12.93924166,7.701211303]
["number of firing neurons in category ","L4 C","L4 MCAO","L4 C","L4 MCAO",null,null,8.3740279799999993,5.42110672,12.160549899999999,7.7823888500000002]
[null,"0 - 5 Hz",null,"5 - 10 Hz",null,null,null,8.99414479,7.4533957300000004,12.6870338,7.8651994500000004]
[null,28,35,23,26,null,null,7.4720959300000001,5.3760599200000003,11.595051700000001,6.5768211599999997]
[null,30,29,16,26]
[null,30,29,19,19]
[null,26,33,24,25]
[null,30,33,23,25]
[null,30,27,25,17]
[null,27,30,22,17]
[null,null,29,null,22]
[null,null,31,null,29]
[{"$nulls":4},20]
[]
[]
[]
[]
[null,"FIGURE 5M"]
[]
["number of firing neurons in category ","L4","L4 + PF8380","L5","L5 + PF8380"]
[null,"WT MCAO 0 - 5 Hz",null,"WT MCAO 5 - 10 Hz"]
[null,23.161629319999999,16.5600877,13.775592189999999,5.6606523500000003]
[null,20.363169060000001,18.548872249999999,12.630555859999999,8.8036208429999991]
[null,21.059120100000001,19.494504599999999,14.250555,8.0861623409999996]
[null,21.799436100000001,17.7784409,14.0801546,6.9882360930000003]
[null,null,19.735454699999998,null,9.2063599200000006]
[]
[]
[]
["number of firing neurons in category ","L4","L4 + PF8380","L5","L5 + PF8380"]
[null,"PRG-1R346T MCAO  0 - 5 Hz",null,"PRG-1R346T MCAO 5 - 10 Hz"]
[null,21.669040800000001,18.591781699999999,15.814509599999999,9.4277433399999993]
[null,22.666362100000001,17.430238729999999,13.14540953,9.7714122900000007]
[null,22.365697999999998,20.395080799999999,10.6772136,6.4137876]
[null,22.8307936,20.682715200000001,13.9014066,7.18575579]
[null,22.6319701,20.031046400000001,11.145315800000001,9.1961361200000002]

{"sheet":"Figure 6","index":5,"n_rows":53,"n_cols":40,"rows_kept":53,"cut":false,"hidden":false,"merged":[[23,1,23,2],[23,3,23,4]]}
[]
[null,"Figure 6C",{"$nulls":10},"Figure 6D"]
[]
["infarct volume (mm3)","vehicle","PF8380 ","vehicle","PF8380 ","vehicle","PF8380 ","vehicle","PF8380 ",null,null,"mNSS","timepoint [h]","vehicle",{"$nulls":12},"PF8380 "]
[null,null,"30 min after MCAO",null,"60 min after MCAO",null,"90 min after MCAO",null,"180 min after MCAO",{"$nulls":17},"30 min after MCAO"]
[null,20.622959999999999,12.28872,35.292000000000002,6.0645600000000002,44.967599999999997,1.7683199999999999,37.408560000000001,15.67944,null,null,null,3,11,8,12,8,13,13,13,12,13,{"$nulls":4},9,13,4,5,12,5,6,5,8,7]
[null,24.299759999999999,13.521839999999999,13.300079999999999,2.86944,48.426720000000003,43.354799999999997,54.908880000000003,42.575519999999997,null,null,null,24,8,8,8,8,11,5,8,11,14,{"$nulls":4},7,12,3,3,6,5,5,4,7,6]
[null,12.18408,1.13784,17.54664,16.685279999999999,47.18112,18.652560000000001,23.669519999999999,14.02464,null,null,null,48,8,5,6,8,6,4,7,8,14,{"$nulls":4},7,8,2,3,5,4,7,3,6,6]
[null,58.099919999999997,3.9864000000000002,25.317119999999999,2.0157600000000002,53.555999999999997,22.20768,59.1492,10.69896,null,null,null,72,8,5,7,8,6,6,7,8,14,{"$nulls":4},6,8,2,4,3,3,5,3,6,5]
[null,82.486559999999997,41.636159999999997,49.27008,6.85128,50.903759999999998,50.043840000000003,62.518079999999998,37.667999999999999]
[null,16.578720000000001,3.9100799999999998,17.762640000000001,2.62608,32.152079999999998,39.631920000000001,36.01728,45.785760000000003]
[null,31.857119999999998,19.169039999999999,34.083359999999999,7.9701599999999999,35.438400000000001,8.7072000000000003,68.629440000000002,54.083759999999998]
[null,59.309280000000001,31.201920000000001,58.70496,6.2450400000000004,54.6432,21.43608,26.11224,43.078800000000001,null,null,"mNSS","timepoint [h]","vehicle",{"$nulls":12},"PF8380 "]
[null,23.499359999999999,9.3938400000000009,51.985439999999997,9.0441599999999998,28.593599999999999,26.64696,42.582720000000002,35.228879999999997,{"$nulls":17},"60 min after MCAO"]
[null,null,11.103120000000001,44.772480000000002,25.012319999999999,21.13776,17.405280000000001,47.151600000000002,24.687840000000001,null,null,null,3,14,8,5,4,8,14,11,13,9,8,7,11,null,6,8,8,9,8,7,8,4,6,8,10]
[null,null,null,39.539520000000003,25.345680000000002,13.90584,17.27496,38.11656,12.37608,null,null,null,24,7,4,5,4,5,12,13,13,13,7,8,14,null,5,5,8,4,5,5,5,3,6,6,4]
[null,null,null,20.376480000000001,null,48.450479999999999,13.072800000000001,{"$nulls":5},48,7,6,4,5,5,9,13,11,13,12,8,14,null,6,3,4,7,5,5,6,2,4,6,7]
[{"$nulls":6},9.1569599999999998,{"$nulls":5},72,7,7,4,5,6,7,14,7,13,12,8,8,null,4,3,4,6,5,4,4,3,5,6,7]
[{"$nulls":6},33.948480000000004]
[]
[]
[{"$nulls":11},"mNSS","timepoint [h]","vehicle",{"$nulls":12},"PF8380 "]
[null,"FIGURE 6E",null,null,"FIGURE 6F",null,null,null,"FIGURE 6F",{"$nulls":17},"90 min after MCAO"]
[{"$nulls":12},3,13,13,14,9,13,7,10,13,7,8,8,13,null,7,8,9,6,8,12,8,8,6,8,12,4,12,14]
["NIHSS (baseline)","Cstroke","PRG-1R346T","NIHSS24","Cstroke","PRG-1R346T",null,"delta NIHSS baseline - 24h","Cstroke","PRG-1R346T",null,null,24,12,7,14,9,12,7,12,13,5,6,10,14,null,12,5,9,5,7,7,8,7,6,4,10,4,7,13]
[{"$nulls":12},48,13,8,13,8,7,7,7,13,4,8,5,14,null,4,5,7,4,5,5,13,7,3,5,7,3,7,13]
[null,9,10,null,3,0,null,null,6,0,null,null,72,13,8,13,13,7,6,7,13,4,13,5,13,null,5,5,6,3,4,4,13,5,3,5,6,3,6,13]
[null,10,7,null,15,7,null,null,-5,8]
[null,5,8,null,0,0,null,null,5,0]
[null,7,15,null,0,15,null,null,7,-2]
[null,8,7,null,3,9,null,null,5,9,null,"mNSS","timepoint [h]","vehicle",{"$nulls":12},"PF8380 "]
[null,7,12,null,0,3,null,null,7,1,{"$nulls":16},"180 min after MCAO"]
[null,14,1,null,0,0,null,null,-5,1,null,null,3,9,13,8,14,12,13,13,8,13,12,13,null,null,13,8,9,11,13,13,13,11,10,13,3]
[null,14,2,null,19,1,null,null,8,-2,null,null,24,10,13,7,13,11,13,13,8,8,11,12,null,null,8,7,7,11,12,13,7,5,5,4,3]
[null,8,6,null,0,8,null,null,8,1,null,null,48,7,13,8,13,12,14,11,7,11,9,13,null,null,8,5,7,11,12,11,6,5,3,6,3]
[null,8,4,null,0,3,null,null,2,4,null,null,72,6,13,8,13,12,13,11,6,10,8,13,null,null,8,4,8,10,12,9,6,5,4,4,3]
[null,13,11,null,11,23,null,null,0,3]
[null,12,4,null,12,0,null,null,1,-1]
[null,3,7,null,2,4,null,null,2]
[null,3,1,null,1,2,null,null,0]
[null,2,null,null,2,null,null,null,0]
[null,2,null,null,2,null,null,null,5]
[null,5,null,null,15,null,null,null,2]
[null,7,null,null,2,null,null,null,1]
[null,5,null,null,3,null,null,null,6]
[null,5,null,null,4,null,null,null,2]
[null,13,null,null,7,null,null,null,5]
[null,12,null,null,10,null,null,null,0]
[null,5,null,null,0,null,null,null,3]
[null,3,null,null,3,null,null,null,3]
[null,5,null,null,2,null,null,null,-1]
[null,5,null,null,2]
[null,1,null,null,2]

{"sheet":"Figure S1","index":6,"n_rows":19,"n_cols":15,"rows_kept":19,"cut":false,"hidden":false,"merged":[]}
[]
[null,"FIGURE S1C",null,null,null,"FIGURE S1D",{"$nulls":5},"FIGURE S1E"]
[]
["Casp3+ cells/mm2","PRG-1R346T","PRG-1R346T PF8380",null,"power in µV2","L4","L4+PF8380","L4","L4+PF8380",null,"coherence","L4","L4+PF8380","L4","L4+PF8380"]
[{"$nulls":5},"theta",null,"gamma",null,null,null,"theta coherence",null,"gamma coherence"]
[null,17.244242499999999,6.17854321,null,null,3.5756005800000001,3.4234701900000002,5.1356823,3.6534568200000002,null,null,0.35590305999999999,0.26748989099999998,0.37818202000000001,0.21115952399999999]
[null,11.757051799999999,2.1753899300000001,null,null,5.92225132,3.7456259900000002,4.5979283300000002,3.48965535,null,null,0.43900361999999998,0.16708959600000001,0.43800663000000001,0.16620690499999999]
[null,11.7888647,1.5130505999999999,null,null,4.5791760999999997,3.8760040099999999,4.5122195600000001,3.9728522399999999,null,null,0.38302022000000002,0.29678458299999999,0.39443304000000001,0.21898134399999999]
[null,10.9025862,2.2694532199999999,null,null,5.5856391199999997,2.2793785600000001,5.7731275899999996,3.74848991,null,null,0.37297012000000002,0.27728950099999999,0.42559141,0.217632413]
[null,6.3985400200000004,3.92603524,null,null,3.9289216200000001,null,4.8936017300000003,null,null,null,0.36139485999999998,null,0.41032964]
[]
[]
[{"$nulls":4},"power in µV2","L4","L4+PF8380","L4","L4+PF8380",null,"coherence","L4","L4+PF8380","L4","L4+PF8380"]
[{"$nulls":5},"PRG-1R346T theta",null,"PRG-1R346T gamma",null,null,null,"PRG-1R346T theta coherence",null,"PRG-1R346T gamma coherence"]
[{"$nulls":5},3.8222473699999999,1.52818615,6.2498387500000003,4.3159872500000001,null,null,0.38109227000000001,0.21993028000000001,0.44619937999999998,0.24047345000000001]
[{"$nulls":5},3.7650993399999999,2.74576069,5.3102650200000001,3.5983372999999998,null,null,0.37284323000000003,0.19884799,0.4040204,0.23998185999999999]
[{"$nulls":5},3.3003045200000001,1.9621907300000001,4.3004987799999999,4.3595934500000002,null,null,0.41519971999999999,0.24453077000000001,0.35302702000000002,0.21726418]
[{"$nulls":5},2.7325186800000001,2.5548679299999999,4.4444852299999997,3.5276290100000001,null,null,0.35661600999999998,0.18454487,0.41963145000000002,0.15531352000000001]
[{"$nulls":5},3.2868810599999998,2.9499839200000002,5.76526899,4.3991564299999997,null,null,0.37754314,0.23698274999999999,0.40197161999999997,0.22707223000000001]