**Bias Evaluation and Reduction in 3D OP-OSEM Reconstruction in Dynamic Equilibrium PET Studies with11C-labeled for Binding Potential Analysis ** Data availability - PONE-D-20-28702 Inside PLOsONE_data folder you will find: a) Folder Bias_Data_Fit: BiasBPnd001 and Phantom002 have respectively BP values and activity concentration values used for the fit - linear regression analysis. b) Excel worksheets 1, 2 and 3 with the reconstruction framing method: - there are informations about true activity in the phantom and quantification accuracy, SE propagation, etc... - These data were used to plot the box plots in OriginPro software