This repository contains a data set of 41 young and 37 old adults and is comprised of
- fully preprocessed resting-state fMRI data (4D
nifti files)
- a list with behavioral data and information on
age and sex

Christian Bäuchl 706c4213aa 'datacite.yml' ändern 6 months ago
RestingState_fMRI_4D 19871fa134 'RestingState_fMRI_4D/101_RESfdswua_REST.nii' löschen 7 months ago
Behavioral_Data.xlsx 23d5ac063e Dateien hochladen nach '' 7 months ago
LICENSE 1bbdc8a280 Initial commit 7 months ago
README.md 40de413aa5 'README.md' ändern 6 months ago
datacite.yml 706c4213aa 'datacite.yml' ändern 6 months ago

README.md

Aging_and_DAT1_interaction_rsfMRI

This repository contains a data set of 41 young and 37 old adults and is comprised of

  • fully preprocessed resting-state fMRI data (4D nifti files)
  • a list with behavioral data and information on age and sex

The names of the resting-state fMRI files have a prefix which indicates whether the subject is a young adult (leading digits start with 1) or an old adult (leading digts start with a 2). The rsfMRI were preprocessed using SPM 12 and FSL and were slice-time corrected, unwarped using a field map, coregistered to individual T1-weighted images, normalized to MNI space and spatially smoothed using a 8 mm FWHM Gaussian kernel. Additional head-motion correction was performed using FSL's ICA-AROMA. Preprocessed functional data were detrended and bandpass-filtered below 0.009 Hz and above 0.08 Hz. Voxelwise regression was used to remove the effects of the mean WM signal and the mean CSF signal from the data.

The file Behavoral_Data.xlsx contains information on age, sex and the individual scores on the Raven's matrices test, the Stroop test (variables: accuracy on incongruent color and reaction time of incongruent color), the spot-a-word test and the identical pictures test.

Datacite.yml
Title Interactive effects of dopamine transporter genotype and aging on resting-state functional networks
Authors Baeuchl,Christian;Chair of Lifespan Developmental Neuroscience, Faculty of Psychology, Technische Universität Dresden, Dresden 01069, Germany;https://orcid.org/0000-0001-5615-3645
Chen,Hsiang-Yu ;Chair of Lifespan Developmental Neuroscience, Faculty of Psychology, Technische Universität Dresden, Dresden 01069, Germany
Su,Yu-Shiang;Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, Taiwan
Hämmerer,Dorothea ;Clinical Neurophysiology and Memory Group, Institute of Cognitive Neuroscience, University College London, WC1N3AR London
Klados,Manousos A. ;Department of Biomedical Engineering, School of Life and Health Sciences, Aston University, Birmingham, B47ET, UK
Li,Shu-Chen ;Chair of Lifespan Developmental Neuroscience, Faculty of Psychology, Technische Universität Dresden, Dresden 01069, Germany
Description The resting-state fMRI data are fully preprocessed and arranged in 4D nifti files. Preprocessing was carried out using SPM 12 (slice-time correction, spatial unwarping, normalizing to MNI space, smoothing with an 8 mm Gaussian kernel) and FSL's ICA-AROMA (additional head-motion correction). Furthermore, the resting-state fMRI data were bandpass filtered (band: 0.009 - 0.08 Hz) and mean WM and CSF signals were regressed out. Behavioral data contain information on age, sex and the individual scores on the Raven's matrices test, the Stroop test (variables: accuracy on incongruent color and reaction time of incongruent color), the spot-a-word test and the identical pictures test.
License Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/)
References
Funding DFG, DFG LI 879/12-2
DFG, DFG SFB 940/2, Project B3
Keywords Resting-state fMRI
Aging
Dopamine transporter gene
DAT1
Graph theory
Functional connectivity
Cognitive testing
Participation coefficient
Brain-behavior correlations
Resource Type Dataset